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Unlike the first study, the researchers

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did see a slight benefit from using the preventive inhaled steroid medication,
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but there were also side effects, such as a smaller gain in height and weight, that probably outweighed those benefits. The children were randomly assigned to receive either a five-day course of between 10 milligrams and 20 milligrams prednisolone depending
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on their age or a placebo for five days. The researchers found no statistically
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significant differences between the two groups using measures such as the duration of hospitalization and the need for additional medications. News Articles 1 Next Article.

"These studies suggest that maybe we don't need to.

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The study of oral
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prednisolone included 700 children between the ages of 10 months and 60 months. Not all wheezing is asthma in kids," Appleyard suggested. "Our study provides robust evidence that a short course of oral
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steroids has no clinical benefit, at least for children with mild to moderately severe [wheezing] attacks," said study senior Benjy Grigg, a professor of pediatric respiratory and environmental medicine at Queen Frances University London. They did this over a period
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of six to
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12 months. Maybe viral-induced wheezing isn't so much inflammation, but an irritability of the airways, so anti-inflammatories [like steroids] don't work.

Babies generally wheeze due to viruses, and in school-aged children, wheeze is often indicative of asthma, but it can be hard to tell the difference in toddlers and preschoolers. The second study, from Canadian doctors, assessed inhaled steroids for wheezing

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associated with a virus, and found that while preventive treatment did reduce the need for rescue medications, the benefits weren't strong enough to outweigh the potential side effects. "These kids have intermittent wheezing with a respiratory virus, with no wheezing in between. Cleaning Products Up Nurses' Asthma Risk Printer-Friendly
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Format Email to a Friend. Children with asthma will wheeze at other times, not just when they have a virus, Appleyard noted. Fluticasone proprionate is an inhaled steroid and is often used as a preventive medication for people with asthma.
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In this study, the children were given the medication or placebo at the onset of any upper respiratory infection and asked to continue the medication for a maximum of 10 days. But, Grigg added, "doctors
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may still prescribe a course [of oral steroids] on a case-by-case basis, especially in severe attacks." The second study included 129 children between the ages of 1 and 6 who were randomly assigned to receive 750 micrograms of inhaled fluticasone proprionate
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One study, from British researchers, looked

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at the use of oral prednisolone and found no significant differences between the treated group of children and those who received a placebo. We're still trying to see if they're just
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they really have asthma, and we've always treated these kids like they have asthma," said Dr. She did point out that the findings from these studies don't apply to children with asthma, and that these medications can be very
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helpful in children with asthma. Maybe we should treat viral-induced wheezing differently." Part of the problem, she explained, is that it can be difficult to tell if small children actually have asthma, or if they're just wheezing from a cold or some other virus.

All had virus-induced wheezing. Gilli Appleyard, chief of allergy and immunology at St. Maybe it's a different pathophysiology with similar symptoms.

The research was published in the issue of the New England Journal of Medicine. "These are kids who are at the brink.



   


















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