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The report was criticized by Dr. "Sertraline is best in terms

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we need to be clear about is that we can't rely on placebo-control trials of new medications done by the industry," Geddes said. In 2006, analysis of the studies
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described in the new journal report led to a labeling change that expanded the warning to young adults. The odds ratio for suicidal behavior declined at a rate of 4.6% for every year of age, according to the study. "In these trials, they compare a drug with a placebo," Geddes said. Arman Geddes,
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England and a co-author of an accompanying editorial in BMJ, who said it relied too much on data from trials sponsored by drug companies.

Information on the suicide risk linked to antidepressant use

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suicide attempts or suicide-related behavior among children
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and adolescents taking the widely used selective serotonin reuptake inhibitors (SSRIs), such as Zoloft, Celexa and Prozac. News Articles 1 Next Article. The analysis revealed eight
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134 suicide attempts and 378 instances of suicidal thoughts that did not lead to action. A review of 372 trials involving nearly 100,000 people who took antidepressants sho that the drugs increase the risk for suicide in people younger than 25, have no effect in those 25 to 64 and reduce risk
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Studies cited in the report indicate that sertraline,

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the generic name for Zoloft, carries only half the risk for suicidal thoughts and behavior of some other SSRIs, Geddes said. "Sometimes
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the clinical questions. A placebo is an inactive substance. The studies show "a bigger picture, where we see a declining rate in older patients that is essentially zero in middle-age adults, and suggest a beneficial
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effect which lowers the risk of suicidal thoughts in older people," Stone said. A report on the findings is published online in BMJ.

We need more active comparison trials which don't have placebo in them and larger trials aimed at antidepressants in clinical practice." Geddes also criticized the report for lumping together all SSRIs. Antidepressant Use Nearly Doubles Printer-Friendly Format Email to a Friend.



   


















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